The book is a portrayal of the adaptation in response to man-made environmental changes on Earth triggered by mutagenic action and polymorphic metamorphosis by the alteration of genetic configuration, which can ensure the survival of a polymorphic species. This work is based on the current understanding of a range of processes which contribute to the return of the peppered moth from the brink of extinction namely the "Reverse Swing", which may play a great role in the macro-evolutionary journey of species. This book contributes to the shifting of our focus from the light of natural selection to the molecular response of the gene against the backdrop of man-made pollution. The book is well written with a historical review of studies, drawing strength from the current work, leading to a comprehensive approach. Care has been taken to select texts most relevant to the topic, demonstrating that the author is familiar with key literature in the field. The level of reference to relevant studies is appropriate, containing coherence and clarity of presentation.